60 capsules · 30-day supply
500 mg NAD+ · 250 mg quercetin · 150 mg trans-resveratrol
Two capsules, morning or evening
Three actives, every dose on the label
Plain packaging, ships from the USA
Supplement facts
- Made in the USA
- Non-GMO, vegan friendly
- Gluten-free
- Three actives, each at its dose
Cellular longevity · 500 mg NAD+ with quercetin and trans-resveratrol
Aging shows up in your cells long before it shows up in the mirror.
NAD+ is what your cells spend on energy and repair, and it falls steadily with age while an enzyme called CD38 consumes more of what's left. NAD+ Advanced answers both halves in one daily pair of capsules: it supplies NAD+, supports the body against what drains it, and supports the sirtuins that spend it.
- Repair that's resourced: supports the cellular repair processes that slow down with age
- The supply: 500 mg NAD+ per serving, printed on the label, never buried in a blend
- The drain: 250 mg quercetin, studied for its effect on CD38, the enzyme that consumes NAD+
- The activator: 150 mg trans-resveratrol for the sirtuins NAD+ powers
- Backed for 60 days: finish the bottle and still get refunded if it didn't earn its place
Step one: the problem
Nobody feels themselves age. They notice that they have.
It never arrives on a particular morning. It's the session that takes two days to shake off instead of one. It's a photograph that looks slightly further along than the face you carry in your head. It's the word that takes a half-second longer to surface.
None of it announces itself. It accumulates quietly for years before it becomes obvious.
Here is what it costs if nothing changes: the pool your repair systems run on keeps falling, and the enzyme draining it keeps climbing. Maintenance that doesn't get resourced gets deferred, and deferred maintenance is what aging fast looks like from the inside.
Which is exactly why it's worth understanding what actually drives it, instead of waiting for the mirror to bring it up.
The root cause
Your cells didn't stop working. Something started draining their fuel.
Every cell you own runs its maintenance and repair work on a coenzyme called NAD+. It's what the sirtuins spend to switch on DNA repair, and what PARP enzymes burn through when damage needs fixing. No NAD+, no repair: the machinery is still there, but it has nothing to run on.
NAD+ falls as you age, and by midlife most people carry markedly less than they did in their twenties.
Here's the part almost nobody is told: it isn't only that you make less of it. An enzyme called CD38 climbs steadily with age, and consuming NAD+ is what CD38 does. The older you get, the more of it you carry, and the faster it drains the pool your repair systems depend on.
That's the root cause. Not willpower, not tiredness, not a vitamin you forgot. A fuel supply being spent faster than it is replaced.
The solution
Three actives. One job each.
Supply the pool. Support the body against what drains it. Support what spends it. Miss any one of the three and the other two do less.
NAD+
The coenzyme itself, at a dose you can read off the label. This is the supply: the fuel your repair machinery actually spends.
Quercetin
One of the best-characterized natural compounds studied for its effect on CD38. This is the part aimed at the drain rather than only the supply.
trans-Resveratrol
A sirtuin activator, from Japanese knotweed at 98% purity. Sirtuins are NAD+-dependent: supporting them only means something if there is a pool to spend.
Yes, send me my first bottle$47 a bottle on subscription, or $59 for a single bottle. 60-day empty-bottle guarantee.
The label
Three actives. Three numbers. Nothing hidden.
NAD+ at 500 mg, quercetin at 250 mg and trans-resveratrol at 150 mg per two-capsule serving, each printed at its dose. No proprietary blend, no total that hides the parts. If you'd rather have the single precursor in one capsule a day, that's our NMN. If you want the whole system addressed, this is it.
- NAD+ (nicotinamide adenine dinucleotide) 500 mg
- Quercetin 250 mg
- trans-Resveratrol (Japanese knotweed, 98%) 150 mg
- Vegetable capsule, no gelatin
- Non-GMO, vegan friendly, gluten-free, lactose-free
- Manufactured in the USA
Why other approaches fall short
Why supply on its own does less than it should
Most of this category tops up the tank and ignores the leak. Here is what that costs, and what this formula does instead.
| The common approach | Where it falls short | NAD+ Advanced |
|---|---|---|
| A single precursor on its own | Supplies the pool and leaves CD38 consuming it at the same rate. Right for the simplest habit; half the system. | Supply and CD38 support in the same capsule |
| Resveratrol on its own | Supports sirtuins that need NAD+ to function: activation with nothing to run on. | Paired with 500 mg of NAD+ |
| Proprietary blends | A longevity matrix at one total weight tells you the sum and hides every dose inside it. | All three actives listed at their milligram |
| Weekly megadoses | Cellular maintenance is daily work, not an event. | Two capsules a day, 30 days to a bottle |
| Stimulant energy formulas | You feel the caffeine, not the repair, and you can't tell the two apart. | No caffeine, no stimulants, nothing you feel in twenty minutes |
Why this works
The combination is the whole point
It treats supply and drain as one problem
Every other formula picks a side. Supplying NAD+ while CD38 keeps consuming it is half a solution, and addressing CD38 with nothing to protect is the other half. Both halves, or neither.
Every dose is checkable
You can read 500 mg, 250 mg and 150 mg straight off the label and compare them against anything else on the shelf. That is a deliberately uncomfortable standard to hold yourself to, and it is the fastest way to tell a serious formula from a marketing one.
It is built for the timescale repair runs on
Two capsules, every day, for months, not a loading protocol or a weekly ritual. The guarantee runs 60 days because that is how long a fair trial takes.
Before and after
What changes, and when
The honest before-and-after here is cellular, not cosmetic. We don't have customer transformation photos, and we're not going to manufacture them.
The declining pool
- NAD+ falling year on year
- CD38 rising and consuming what's left
- Sirtuins short of the fuel they need
- Repair work quietly deferred
The supported pool
- 500 mg of NAD+ supplied, daily
- The drain addressed, not only the supply
- Sirtuins supported and supplied
- Maintenance work resourced
- Days 1 to 7 Nothing dramatic The honest answer: most people feel nothing in week one. This is not a stimulant, and anything that hits you on day one probably is.
- Weeks 2 to 3 The quiet stretch Where most people quit. Nothing visible has changed, so it feels like nothing is happening. You're a third of the way through a fair trial.
- Weeks 4 to 6 The sideways notice People tend to notice this one indirectly: a session that didn't cost as much the next day, an afternoon that didn't sag.
- Week 8 The honest test Two bottles is a fair trial. If it hasn't earned its place by day 60, that is exactly what the guarantee is for. Email us before the 60 days are up.
Individual results vary. This describes what these ingredients are understood to do in the body. It is not a promise about what you will experience.
Start my first 60 days$47 a bottle on subscription, or $59 for a single bottle. 60-day empty-bottle guarantee.
Proof
What's established, and what isn't
We'd rather show you the line between the two than blur it.
- Manufactured in the USA
- Non-GMO
- Vegan friendly
- Gluten-free
- Lactose-free
- Corn-free
- Hormone-free
- Antibiotic-free
- Three actives, each at its dose
These statements describe the published biology of the ingredients. They are not claims about clinical trials of this product; no trial of this formula has been run, and we won't imply otherwise. These statements have not been evaluated by the Food and Drug Administration.
The goal isn't living forever. It's still being yourself at seventy.
Nobody gets to skip aging. But the gap between aging well and aging fast is mostly maintenance: whether the repair systems you already have are resourced well enough to keep up with the damage. NAD+ is what they run on, CD38 is what drains it, and this is the daily habit that answers both. The outcome is quieter than a number: a session that doesn't cost you the next day, an afternoon that holds, and a routine so small you stop thinking about it.
Send me my first bottle$47 a bottle on subscription, or $59 for a single bottle. 60-day empty-bottle guarantee.
How to use it
Two capsules. That's the entire protocol.
- Take two capsules dailyWith about 6 oz of water. Morning or evening, consistency matters far more than timing.
- With food or withoutNeither helps nor hurts enough to plan your day around it. Take them when you will actually remember.
- Give it two bottlesRepair compounds. One bottle tells you very little; two tells you what you need to know.
- Store cool and dryAnd don't use it if the safety seal is missing or damaged.
Do not exceed the recommended dose. Not for anyone pregnant, nursing or under 18. If you're managing a medical condition or taking prescription medication, speak to your physician before starting this or any dietary supplement.
The 60-Day Empty-Bottle Guarantee
Take it every day. Finish the bottle, or both bottles if you ordered two or subscribed. If, within 60 days of your first delivery, you don't think it earned its place in your routine, tell us and we refund every bottle from that order, empty bottles and all.
We'd rather carry that than have you judge a formula that works on a 60-day timescale by how you feel after a week.
Send me my first bottleEmail hello@mediclab.us within 60 days of your first delivery. That's the whole process.
Daily cellular support for less than a coffee a day
The goal was never a supplement. It's reaching 60 still recognizably yourself: still sharp, still recovering, still not thinking about it.
- 60 capsules: 500 mg NAD+, 250 mg quercetin, 150 mg trans-resveratrol30 days
- 20% off every bottle on subscription$47 instead of $59
- The 60-Day Empty-Bottle Guaranteeincluded
- Pause, skip or cancel from your accountincluded
- One bottle a month, everything abovethe price below
Bought separately, NAD+, a CD38-targeted flavonoid and a sirtuin activator are three bottles and three decisions every morning. Here they are one label at three printed doses.
Against a blend that prints one total and hides every dose inside it, this is checkable in ten seconds and backed for 60 days.
That is $1.57 a day on subscription, for the fuel repair runs on.
Start my subscription60-day empty-bottle guarantee. Ships from the USA in a plain box.
Ships from the USA. Your card is charged the price shown above plus shipping at checkout, nothing hidden, and no trial that quietly converts into something bigger.
Reviews
Reviews, published as we receive them
Bought NAD+ Advanced? Email your review to hello@mediclab.us, with a photo of your bottle if you like, and we publish it exactly as written.
We publish reviews exactly as they are written, and we don't publish any we haven't actually received. Customer photos are shown as sent, unedited.
What you might be thinking
The six things people think before they order
Answered plainly, in the order people usually think them.
Because the pool doesn't wait for you to feel it. NAD+ falls a little every year, CD38 climbs a little every year, and the maintenance they fund gets deferred long before anything shows. The people who get the most out of daily support are the ones who start while there is the most left to protect.
So have we, which is why all three actives are printed at their milligram and why the guarantee runs 60 days instead of 30. Finish the bottle, or both. If it didn't earn its place, you get every dollar of that order back, empty bottles and all.
It's a different route to the same pool, and we sell both. NMN is the single precursor in one capsule a day: the simplest habit. NAD+ Advanced supplies NAD+ itself and adds quercetin for the enzyme that consumes it and resveratrol for the sirtuins that spend it: the whole system in one label. Pick the one that matches how you like to do things; you don't need both.
It's better known for immune support, but it is also one of the best-characterized natural compounds studied for its effect on CD38, the enzyme that climbs with age and consumes NAD+. Supplying NAD+ without addressing what consumes it only does half the job.
Probably not in week one, and that's the expected answer. Nothing here is a stimulant. Most people notice it sideways, weeks in: a session that didn't cost as much the next day, an afternoon that didn't sag. Feeling a supplement and benefiting from one are different things.
From your account, whenever you like. No phone call, no retention script. Pause, skip or cancel, and if it isn't working for you we'd rather you stopped. Or skip the subscription and buy a single bottle; the guarantee is the same either way.
Send me my first bottle60-day empty-bottle guarantee. Ships from the USA in a plain box.
Questions
What people ask before they order
Is this an anti-aging pill?
No, and anyone selling you one of those is lying to you. This is a daily supplement that supports the cellular machinery your body already uses to maintain and repair itself. That machinery runs on NAD+, NAD+ declines with age, and this supplies some of it while addressing what drains it. That's the honest scope, and it's a bigger deal than it sounds.
How is this different from NMN?
NMN is a precursor: one molecule, one capsule, and your body makes the NAD+. This supplies NAD+ itself, plus quercetin for CD38, the enzyme that consumes it, and resveratrol for the sirtuins that spend it. Both are legitimate routes and we sell both. If you want the simplest habit, our NMN is that product. If you want the whole system addressed, this is the one.
Why quercetin? I thought that was for allergies.
It's better known for immune support, but it is also one of the best-characterized natural compounds studied for its effect on CD38, the enzyme that climbs with age and consumes NAD+. Supplying NAD+ without addressing what's consuming it only does half the job.
When will I notice something?
Probably not in the first week, and that is the expected answer rather than a disappointing one. See the timeline above. Two bottles is a fair trial, which is precisely why the guarantee runs 60 days rather than 30.
Is it third-party tested?
We don't currently publish a third-party certificate of analysis, and we're not going to claim one we can't show you. What we can tell you is that it's manufactured in the USA and every active is printed at its dose on the label.
Can I take it alongside my other supplements?
Usually, yes, but we're in no position to know what else you take. Ask your physician, particularly if you're on prescription medication.
Does it contain caffeine or stimulants?
Neither. If you want something you feel twenty minutes after swallowing it, this isn't that product. Feeling a supplement and benefiting from one are different things.
Who shouldn't take this?
Anyone under 18, anyone pregnant or nursing, and anyone managing a medical condition without speaking to their physician first.
How do I cancel the subscription?
From your account, whenever you like. No phone call and no retention script. If it isn't working for you we'd rather you stopped.
What happens after I click Buy it now?
You go straight to a secure checkout with the plan you selected in it. Use Send me my first bottle instead if you want to add another product before checkout. Your card is charged the price shown plus shipping, and it only recurs if you chose Subscribe & Save.
What if it doesn't work for me?
Finish the bottle and tell us within 60 days of your first delivery. Full refund on every bottle from that order, empty bottles and all.
Send me my first bottle$47 a bottle on subscription, or $59 for a single bottle. 60-day empty-bottle guarantee.
If you need us
A real person, in your inbox
Before you order is a perfectly good time to ask.
Send me my first bottle$47 a bottle on subscription, or $59 for a single bottle. 60-day empty-bottle guarantee.
P.S. Your NAD+ is lower today than it was a year ago, and that carries on whether or not you do anything about it. Three actives at printed doses, $47 a bottle on subscription or $59 for a single bottle, and the first 60 days are covered by the guarantee: finish the bottle and still get refunded if it didn't earn its place.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results vary. Consult your physician before starting any dietary supplement, particularly if you are pregnant, nursing, under 18, or taking prescription medication.
